Plumeria can be grown in a desert climate, but it requires specific care. Provide the plant with ample sunlight and partial shade during the hottest part of the day to protect it from scorching. Water your Plumeria deeply but infrequently to withstand dry conditions. Use a well-draining soil mix and add organic matter to improve water retention. Applying mulch around the base of the plant can also help retain soil moisture. Ensure proper ventilation and air circulation to reduce humidity, which can lead to fungal diseases. With proper care, Plumeria can thrive in a desert climate and produce beautiful flowers.