Yes, all parts of the Plumeria plant are considered toxic if ingested. The sap of Plumeria contains milky latex, which can cause skin irritation in some individuals. Ingestion of any part of the plant can lead to stomach upset and digestive issues. It’s essential to keep Plumeria away from pets and small children to prevent accidental ingestion. When handling the plant or pruning, it’s advisable to wear gloves to avoid contact with the sap. Plumeria toxicity is relatively mild, but caution should still be exercised to prevent any adverse reactions.